KIM, Hye Joo,YU, Ji-Yeon,LEE, Dong In,KANG, Yusun,PARK, Hee Kyung
申请号:
AU2019219473
公开号:
AU2019219473A1
申请日:
2019.01.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present invention relates to: a skin-permeating carrier containing a novel-structured nucleic acid complex for enabling a bioactive nucleic acid to be introduced into a cell; and a composition comprising same, for diagnosing, preventing or treating a disease. More specifically, the present invention relates to: a skin-permeating carrier exhibiting skin permeability and skin retention, and containing a nucleic acid complex having a bioactive nucleic acid complementarily bound with a carrier peptide nucleic acid; and a composition comprising same, for diagnosing, preventing or treating a disease. According to the present invention, the skin-permeating carrier containing the nucleic acid complex having a structure represented by structural formula (1) has, simultaneously,