A medical infusion filter including a box body defined by at least two half shells coupled to define an internal cavity divided into at least two chambers by at least one hydrophilic filtering membrane. These chambers include at least one first or entry chamber and at least one second or exit chamber. The at least one first or entry chamber connected to an entry conduit for the medical fluid originating from a corresponding container. The at least one second or exit chamber connected to an exit conduit. At least the first or entry chamber is within a first half shell presenting at least one aperture within which a corresponding hydrophobic membrane is positioned. The at least one aperture enables a differential air flow rate to pass towards the exterior of the box casing as a function of distance of the casing air exit zone from the entry conduit.