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3,5- (U) SUBSTITUTED-1H-PYRROLO [2,3-B] PYRIDINE, 1H-PYRAZOLO [3,4-B] PYRIDINE AND 5H-PYRROLO [2-, 3-B] PYRAZINE-DUAL- ITK AND JAK3 KINASE INHIBITORS
专利权人:
Arrien Pharmaeuticals LLC
发明人:
Vankayalapati, Hariprasad,YERRAMREDDY, Venkatakrishnareddy,GANGIREDDY, Paramareddy,APPALANENI, Rajendra, P.
申请号:
DK14784823
公开号:
DK2986300T3
申请日:
2014.04.17
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
The present invention relates to compounds described by Formula I:salts thereof, their synthesis, and their use as ITK and JAK3 inhibitors including such compounds and methods of using said compounds in the treatment of various diseases and or disorders such disease associated with abnormal cell growth such as autoimmune, inflammation, rheumatoid arthritis, systemic lupus erythematosus, atherosclerosis, ulcerative colitis, psoriatic arthritis, psoriasis, Crohn's, metabolic and cancer diseases. The present invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions and processes for preparing the compounds of the invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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