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SERUM ANTIBODY ASSAY FOR DETERMINING PROTECTION FROM MALARIA, AND PRE-ERYTHROCYTIC SUBUNIT VACCINES
专利权人:
Sanaria Inc.;Antigen Discovery, Inc.;The United States of America, as represented by the Secretary, Department of Health and Human
发明人:
Philip FELGNER,Stephen L. HOFFMAN,Robert SEDER,Joseph J. CAMPO, Jr.
申请号:
US15060959
公开号:
US20160320404A1
申请日:
2016.03.04
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed herein are diagnostic methods and compositions for identifying individuals that are protected against Plasmodium falciparum caused malaria. Such methods are particularly useful for determining not only the protective efficacy of Pf whole parasite vaccines for individual subjects, but also within populations of vaccinated subjects. Also disclosed herein are subunit vaccines comprising at least one Pf immunologic determinant for protection against Plasmodium-caused malaria.
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