稠合三環γ-胺基酸衍生物鹽類之晶型、製備方法及其用途农业专利-农业专业知识服务系统

发明人:: LI, YAO,李瑶,李瑤,SHI, ZONGJUN,石宗军,石宗軍,SHI, SHAOHUI,史少辉,史少輝,LI, SHENG,李升,YAN, PANGKE,严庞科,嚴龐科,ZHENG, WEI,郑伟,鄭偉

摘要：: The present invention provides salts and/or crystal forms of condensed tricyclic γ-amino acid derivatives and their preparation and application. As shown in formula (I), wherein Y is selected from maleic acid, fumaric acid, hydrohalic acid (preferably hydrobromic acid and hydrochloric acid), sulfuric acid, phosphoric acid, L-tartaric acid, citric acid, L-apple Acid, hippuric acid, D-glucuronic acid, glycolic acid, mucic acid, succinic acid, lactic acid, orotic acid, pamoic acid, malonic acid, gentisic acid, oxalic acid, glutaric acid or saccharin: .本發明提供了稠合三環γ-胺基酸衍生物的鹽和/或晶型及製備和應用。所述如式（I）所示，其中，Y選自馬來酸、富馬酸、氫鹵酸（優選為氫溴酸和鹽酸）、硫酸、磷酸、L-酒石酸、檸檬酸、L-蘋果酸、馬尿酸、D-葡萄糖醛酸、乙醇酸、粘酸、琥珀酸、乳酸、乳清酸、帕莫酸、丙二酸、龍膽酸、草酸、戊二酸或糖精：。