The invention relates to a medical imaging device, comprising acquisition means (14, 15, 17, 26, 74) by X-ray adapted for acquisition of data representative of an object (16), an ultrasound probe (10) capable of being shifted manually by a user, processing means (32) adapted to: produce at least one image of the object from data acquired by the X-ray acquisition means, and determine a path between a position of the ultrasound probe and a position in the object corresponding to a selected zone in said image, guide means (20) of the ultrasound probe, said guide means being adapted to facilitate shifting the probe along the path between a position of the ultrasound probe and the position in the object corresponding to the selected zone in said image.