Disclosed is the seed of a novel soybean variety, designated AM10995468, asampleof which is deposited under ATCC Accession No. PTA-123619. Also disclosed areplants, orparts thereof, grown from the seed of the variety, plants having themorphological andphysiological characteristics of the AM10995468 variety, and methods of usingthe plant orparts thereof in a soybean breeding program. The invention also relates tocells and uses ofsoybean variety AM10995468.