KNC Laboratories Co., Ltd.;National University Corporation Nagoya University;Osaka University
发明人:
申请号：
EP18832760.5
公开号：
EP3653711A1
申请日:
2018.07.06
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention provides a suppression type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in any of SEQ ID NOs: 2 - 4, and a promotion type antisense oligonucleotide targeting TDP-43 mRNA, containing a nucleotide sequence complementary to a sequence consisting of at least 10 continuous nucleotides in a nucleotide sequence shown in SEQ ID NO: 5.
