The invention provides a solution to the above mentioned problem in that it provides a catheter balloon comprising a flexible coating on its outer surface wherein a plurality of microparticles are contained wherein said coating comprises a material selected from the group consisting of poly(N-vinyl-pirrolidone, poly(N-vinyl- pirrolidone-co-butylacrylate), poly(4-vinyl pyridine), polyacrylamides, e.g. poly(N- isopropylacrylamide), poly(amido-amines), poly(ethylene imine), poly(ethylene oxide- block-propylene oxide), poly(ethylene oxide-block-propylene oxide-block-ethylene oxide), poly(styrene-block-isobutylene-block-styrene), poly(hydroxystyrene-block- isobutylene-block-hydroxystyrene), polydialkylsiloxanes, polysaccharides, polyacrylates and polyalkylmethacrylates, e.g. polymethylmethacrylate and poly(2- hydroxyethylmethacrylate) and wherein said microparticles comprise a material selected from the group consisting of polyesters, e.g. poly(lactic acid), poly(lactic-co- glycol acid), poly(glycolic acid), poly(3-hydroxybutyrate), poly(3-hydroxyvalerate), poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and polycaprolactone, polyamides, polysaccharides, polyurethanes, polyalkylmethacrylates and polyacrylates, e.g. polymethylmethacrylate and poly(2-hydroxyethylmethacrylate) and wherein the microparticles comprise a pharmaceutically active compound.Linvention concerne un ballonnet de cathéter qui comprend un revêtement flexible sur sa surface extérieure dans lequel sont contenues une pluralité de microparticules. Le revêtement contient un matériau sélectionné dans le groupe comprenant poly(N-vinyl-pirrolidone, poly(N-vinyl- pirrolidone-co-butylacrylate), poly(4-vinylpyridine), polyacrylamides, e.g. poly(N- isopropylacrylamide), poly(amido-amines), poly(éthyléneimine), poly(oxyde déthylène-oxyde de propylène), poly(oxyde déthylène-oxyde de propylène-oxyde déthylène), poly(styrène-isobutylène-styrène), poly(hydroxystyrène-isobutylène-hydroxystyrène), polydialkylsiloxanes, poly
