Marie Cumberbatch;Ian Kimber;Rebecca Jane Dearman;Russell Colin Viner
发明人:
Marie Cumberbatch,Rebecca Jane Dearman,Ian Kimber,Russell Colin Viner
申请号:
US12086210
公开号:
US08188053B2
申请日:
2006.12.04
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates, inter alia, to a method of ameliorating an inflammatory skin condition. Thus, the present invention provides a peptide that includes the amino acid sequence KMIKP (SEQ ID NO: 20), wherein the peptide includes no more than 70 amino acids and wherein the peptide is capable of inhibiting allergen induced Langerhans cell migration, and wherein the peptide is not that depicted in SEQ ID NO. 19. The present invention also relates to the use of a peptide that includes the amino acid sequence KMIKP (SEQ ID NO: 20), wherein the peptide includes no more than 100 amino acids, and wherein the peptide is capable of inhibiting allergen induced Langerhans cell migration, in the manufacture of a topical medicament for the treatment of an inflammatory skin condition.