An instrument for inserting a suppository which includes a tube, having a first end adapted to receive the suppository and a second end, and a plunger disposed in the tube and moveable therein to eject the suppository from the first end by causing an action of pushing the suppository from behind. Retaining tongues are splayed outwards for ejection of the suppository in response to movement of the plunger in the tube, via contacting cooperation between at least one part of the plunger and at least one part of the tube. Securement mechanism secure the plunger in the tube at first position in which the suppository is retained in the first end of the tube, while allowing a user to move the plunger to actuate the instrument, and to secure the plunger in the tube at a second position which is only achievable after the plunger has been moved to eject the suppository.
