Specific binding members that bind the ED-A isoform of fibronectin for use inmethods of diagnosis, detection,imaging and/or treatment of endometriosis, and/or for use in delivery to theneovasculature of endometriotic tissue of a moleculeconjugated to the specific binding member. Specific binding members that bindtenascin-C, especially the A1 A2, A3, A4 and/orD domain tenascin-C large isoform, for use in methods of diagnosis, detection,imaging and/or treatment of endometriosis, psoriaticathritis or psoriasis, and/or for use in delivery to the neovasculature ofendometriotic, psoriatic arthritic or psoriatic tissue ofa molecule conjugated to the specific binding member.