A method comprising detecting an epileptic event in a patient； applying an electrical therapy to a first target area in at least one of a brain region or a cranial nerve of said patient in response to said detecting； receiving a body signal responsive to the electrical therapy, wherein said body signal is selected from an autonomic signal, a neurologic signal, a metabolic signal, an endocrine signal, or a tissue stress marker signal； determining whether said body signal indicates that said electrical therapy has an efficacious effect； and terminating the application of said electrical therapy if the response indicates that the electrical therapy has an efficacious effect. An apparatus capable of performing the method. A non-transitive, computer-readable storage device for storing data that when executed by a processor, perform the method.
