HOERR, INGMAR,PASCOLO, STEVE,VON DER MUELBE, FLORIAN
申请号：
CA2457959
公开号：
CA2457959C
申请日:
2002.06.05
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to a pharmaceuticalcomposition containing an mRNA that is stabilised bysequence modifications in the translated region and isoptimised for the translation. The pharmaceuticalcomposition according to the invention is particularlysuitable as an inoculating agent as well as a therapeuticagent for tissue regeneration. In addition a process isdescribed for determining sequence modifications that servefor the stabilisation and translation optimisation of mRNA.
