您的位置: 首页 > 农业专利 > 详情页

DERIVE DE 1 2 DIHYDROQUINOLINE A ACTIVITE DE FIXATION DU RECEPTEUR DES GLUCOCORTICOIDES GLUCOCORTICOIDES
专利权人:
LTD.;SANTEN PHARMACEUTICAL CO.
发明人:
MATSUDA, MAMORU,MORI, TOSHIYUKI,KAWASHIMA, KENJI,NAGATSUKA, MASATO,KOBAYASHI, SACHIKO,YAMAMOTO, MINORU,KATO, MASATOMO,TAKAI, MIWA,ODA, TOMOKO
申请号:
CA2621292
公开号:
CA2621292C
申请日:
2006.09.14
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
An object of the present invention is to study synthesisof a novel 1,2-dihydroquinoline derivative and to find apharmacological action of the derivative. A compoundrepresented by the general formula (1) or a salt thereof iseffective in the treatment of a glucocorticoidreceptor-related disease. In the formula, the ring Xrepresents a benzene ring or a pyridine ring; R1 representsa halogen atom, an alkyl group, a hydroxy group, an alkoxygroup, an amino group or the like; p represents an integerof 0 to 5; R2 represents a halogen atom, an alkyl group, ahydroxy group or the like; q represents an integer of 0 to2; R3 represents a hydrogen atom, an alkyl group, an alkenylgroup or the like; R4 and R5 represent a hydrogen atom or thelike; R6 represents a hydrogen atom or the like; A representsan alkylene group or the like; and R7 represents OR8, NR8R9,SR8, S(O)R8 or S(O)2R8, wherein R8 represents an aryl group,a heterocyclic group or the like and R9 represents a hydrogenatom or the like.(see formula 1)
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充