A sterile adapter assembly (303) is disclosed herein. The sterile adapter assembly (303) comprises of a housing (401) and a floating plate (423) positioned within the housing (401). The sterile adapter assembly further comprises of at least one rotatable body (505a) having a circumferential surface affixed on the floating plate (423). The at least one rotatable body (505a) having at least one opening (601a) capable of receiving at least one pin of a driving element (413) of an actuator assembly (305). The sterile adapter assembly further comprises of a compression mechanism (700) positioned inside the at least one rotatable body (505a) to align the at least one pin of the driving element (413) of the actuator assembly (305) with the at least one opening (601a) of the at least one rotatable body (505a).
