Andrew Leach,Jeffrey James Morris,Paul David Johnson,Richard William Arthur Luke,Zbigniew Stanley Matusiak
申请号:
BRPI0818533
公开号:
BRPI0818533A2
申请日:
2008.10.09
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The invention relates to a novel group of compounds of Formula (I) or salts thereof: wherein Y, Z1, Z2, R1, R4, R5 and n are as described in the specification, which may be useful in the treatment or prevention of a disease or medical condition mediated through protein kinase B (PKB) such as cancer. The invention also relates to pharmaceutical compositions comprising compounds of Formula (I), methods of treatment of diseases mediated by PKB using said compounds and methods for preparing compounds of Formula (I).