Systems and methods suitable for decreasing catheter-associated bacteriuria in a catheterized patient include a urinary collection system having a collection bag, a drain tube fluidically connected to the collection bag to enable emptying urine collected in the collection bag, and a flexible continuous tube formed as an integral one-piece component and fluidically connected to the collection bag to enable urine to flow into the collection bag from a patient's bladder. Catheter- associated bacteriuria may be decreased in the system by instilling a sterile acetic acid solution into the collection bag via the continuous tube, dispersing the solution in the collection bag, draining the solution from the collection bag via the drain tube, and then allowing urine to flow from the catheterized patient through the continuous tube and into the collection bag.