The embodiments include methods of treating conditions requiring removal or destruction of cellular elements, such as benign or malignant tumors in treatment naive mammals, using compounds based on small peptides derived from Neural Thread Protein. The best exemplified condition to be treated is benign prostatic hyperplasia. The method includes, but is not limited to, administering the compounds intramuscularly, orally, intravenously, intrathecally, intratumorally, intranasally, topically, transdermally, etc., either alone or conjugated to a carrier to a naive mammal in need thereof who had not previously been treated for the condition.