In one example, a therapy system includes a sleeve that defines an opening and has an outer surface and an inner surface. A therapeutic device is positioned so that the inner surface of the sleeve is disposed between the therapeutic device and an extremity of a user when the extremity is positioned in the opening defined by the sleeve. A manually operable tightening mechanism is provided that includes a lace connected to first and second portions of the outer surface of the sleeve and the lace is engaged with a mechanical lace tensioner that is operable to change, by either drawing the first and second portions toward each other or by allowing the first and second portions to move away from each other, a magnitude of a compressive force exerted by the sleeve on the extremity when the extremity is positioned within the opening defined by the sleeve.
