Charles Antzelevitch,Luiz Belardinelli,Alexander Burashnikov,John Shryock,Dewan Zeng
申请号:
US13907349
公开号:
US20130317038A1
申请日:
2013.05.31
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a method for the treatment or prevention of atrial fibrillation and/or atrial flutter comprising coadministration of a synergistically therapeutic amount of dronedarone or a pharmaceutically acceptable salt or salts thereof and a synergistically therapeutic amount of ranolazine or a pharmaceutically acceptable salt or salts thereof. Also provided are methods for modulating ventricular and atrial rhythm and rate. This invention also relates to pharmaceutical formulations that are suitable for such combined administration.