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quinoxaline compounds, pharmaceutical compositions containing them and use of said compositions
专利权人:
FUNDAÇÃO UNIVERSIDADE ESTADUAL DE MARINGÁ;GLAXOSMITHKLINE BRASIL LTDA.;UNIVERSIDADE FEDERAL DE SÃO CARLOS
发明人:
ARLENE GONÇALVES CORRÊA,CELSO VATARU NAKAMURA,DIEGO PEREIRA SANGI,JEAN HENRIQUE DA SILVA RODRIGUES,JULIANA COGO,MARCIO WEBER PAIXÃO,VANESSA KAPLUM
申请号:
BR102013030329
公开号:
BR102013030329A8
申请日:
2013.11.26
申请国别(地区):
BR
年份:
2019
代理人:
摘要:
quinoxaline compounds, pharmaceutical compositions containing them and use of said compositions. quinoxaline compounds are described according to the formula where r1 is selected from the group consisting of cl, aryl, or nhr, where r is selected from the group consisting of me, et, abu, 'bu, cyclohexiia, phenyl, ch2ch2oh; r2 is selected from the group consisting of arila, nhr, sme, some, so2me; r3 is selected from the group consisting of h, f, cl, br, ome; and r4 is selected from the group consisting of h, ome, cl. pharmaceutical compositions containing compounds according to the invention, with activity for epimastigote, intracellular amastigote and trypomastigote forms of ttypanosoma cruzi and promastigote and intracellular amastigote forms of leishmania amazonensis, are also described.compostos de quinoxalina, composições farmacêuticas contendo os mesmos e uso das ditas composições. são descritos compostos de quinoxalina de acordo com a fórmula onde r1 é selecionado dentre o grupo consistindo de cl, arila, ou nhr, onde r é selecionado dentre o grupo consistindo de me, et, abu, 'bu, ciclohexiía, fenila, ch2ch2oh; r2 é selecionado dentre o grupo consistindo de arila, nhr, sme, some, so2me; r3 é selecionado dentre o grupo consistindo de h, f, cl, br, ome; e r4 é selecionado dentre o grupo consistindo de h, ome, cl. são igualmente descritas composições farmacêuticas contendo compostos de acordo com a invenção, com atividade para formas epimastigota, amastigota intracelular e tripomastigota de ttypanosoma cruzi e formas promastigota e amastigota intracelular de leishmania amazonensis.
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中国工程科技知识中心
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http://www.ckcest.cn/home/
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