Medical Research Council;Cambridge Enterprise Limited
发明人:
Edward CHOUCHANI,Thomas KRIEG,Michael Patrick MURPHY,Lorraine WORK,Christian FREZZA
申请号：
US15322939
公开号：
US20170135977A1
申请日:
2015.07.03
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The invention relates to a succinate dehydrogenase inhibitor or a prodrug and/or a pharmaceutically acceptable salt thereof for use in the treatment or prevention of reperfusion injury, such as ischemia-reperfusion injury, by inhibiting the accumulation of succinate, wherein the inhibitor or prodrug and/or pharmaceutically acceptable salt thereof is a cell-permeable reversible inhibitor of succinate dehydrogenase.
