ALMASSY ROBERT,SHOWALTER RICHARD E,THOMSON JAMES A,SISSON WES,SHIA WEI JONG,Chen li chang,YANG LEE
申请号:
IN7802/DELNP/2015
公开号:
IN2015DN07802A
申请日:
2015.08.31
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention relates generally to isolated to arginine deiminase (ADI) proteins that have reduced cross reactivity with anti ADI PEG 20 antibodies as compared to ADI PEG 20 but which can have functional characteristics comparable to or better than ADI PEG 20 compositions comprising the ADI proteins and related methods of treating arginine dependent diseases or related diseases such as cancer.