improved synergistic composition； method of prophylactic or therapeutic treatment of diabetes； method of improving the effectiveness of treating sulfonylurea diabetes in an individual receiving sulfonylurea antidiabetic therapy； method of treating hyperglycemia； and method of preventing development or amelioration of side effects or conditions in an individual treated with a sulfonylurea and / or a sulfonamide and / or derivatives and / or metabolites thereof.
The present invention is concerned with improved synergistic compositions effective in the treatment of diabetes and/or hyperglycemia. In particular, the present invention is concerned with synergistic compositions comprising inulin preparations having a defined degree of polymerisation (DP) of below about 25 and sulfonylureas and/or a sulfonamide and/or derivatives and/or metabolites thereof used in the treatment of Type-2 Diabetes Meliitus (T2DM). Said compositions are also used for preventing the development of, or ameliorating, side-effects or conditions in a subject treated with sulfonylurea and/or a sulfonamide compounds (and/or derivatives and/or metabolites thereof, or combinations thereof), said side-effects including hypoglycemia, gastrointestinal disturbances, fatigue, weight gain, and satiety.
