LIN, SHINN ZONG,林欣荣,林欣榮,HARN, HORNG JYH,韩鸿志,韓鴻志,LIU, SHIH PING,刘诗平,劉詩平,FU, RU HUEI,傅如辉,傅如輝,LIN, PO CHENG,林珀丞,林珀丞,CHUANG, MING HSI,庄明熙,莊明熙
申请号：
TW104119530
公开号：
TW201612314A
申请日:
2014.09.17
申请国别(地区):
TW
年份:
2016
代理人:
摘要：
A use of ligustilide is provided, including the use of ligustilide to enhance the therapeutic effect of stem cells on treating autoimmune diseases, cardiovascular diseases, and/or hematological diseases, as well as the use of a combination of ligustilide and ligustilide-treated stem cells on the aforementioned stem cell therapy. With the treatment of ligustilide, stem cells can provide an enhanced therapeutic effect. Such treatment especially can increase the expression of differentiation-promoting genes in stem cells, increase the expression of homing-promoting genes in stem cells, and/or decrease the expression of inflammatory genes in stem cells.藁本內酯(ligustilide)之應用,包括使用藁本內酯以提升幹細胞於治療自體免疫疾病、心血管疾病、及/或血液性疾病之效益,以及於前述幹細胞治療上併用藁本內酯與經藁本內酯(ligustilide)處理之幹細胞的應用。經由以藁本內酯處理幹細胞,可提升幹細胞的治療效益,尤其可增加幹細胞之促進分化之基因的表現、增加該幹細胞之促進回歸(homing)之基因的表現、及/或降低該幹細胞之發炎基因的表現。
