Dina Brady ANDERSON,Gavin Stephen HACKETT,Sai Man LIU
申请号：
US15540637
公开号：
US20180141982A1
申请日:
2015.01.09
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Engineered clostridial toxins comprising an amino acid modification that increases the isoelectric point of the engineered clostridial toxin to a value that is at least 0.2 pI units higher than the isoelectric point of an otherwise identical clostridial toxin lacking the modification, wherein the modification is not located in the clostridial toxin binding domain (HC domain).
