Provided herein is an antimicrobial composition having at least one free fatty acid or a derivative and/or a pharmaceutically acceptable salt thereof, wherein the free fatty acid has from 6 to 16 carbon atoms, at least one carboxylic acid or a pharmaceutically acceptable salt thereof and/or at least one carbohydrate or a pharmaceutically acceptable salt thereof, wherein the carbohydrate is selected from a hydrogenated carbohydrate, a monosaccharide, a disaccharide, a polysaccharide and combinations thereof. The antimicrobial composition provides enhanced anti-adhesion and/or disinfecting properties. The composition of the present invention can be formulated into a drink, gel or spray suitable for treating or preventing the first stage in pathogenesis.