POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS

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专利权人:

发明人:

申请号：

EP14726731.4

公开号：

EP2999711A1

申请日:

2014.05.21

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

Described are compounds of formula (I) for use in combination treatment with a second active agent, such as rifampicin, for example for treatment of a microbial infection. The compound of formula (I) is a polymyxin compound is: where the groups -A-, —R1, —R2, —R3, —R4, —R5, —R6, —R7, —R8, and —X— are described in detail within the description.

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