The invention relates to a dose reset mechanism to be used in a medicament delivery device, wherein the dose reset mechanism comprises a dose setting member (10) arranged in a housing for setting a dose when it is rotated and for resetting a dose when it is rotated in the opposite direction. A drive member (38) is connected to plunger rod (41) such that when said drive member is rotated, the plunger rod is axially moved, acting on a container for expelling the medicament. A connection member (26) is arranged between the dose setting member and the drive member. The connection member and the drive member are interconnected by ratchet means (34,44) such that the connection member is also rotated when the dose setting member is rotated but locked by the ratchet means from being moved in the opposite direction. The dose setting member further comprises at least one dose reset member (18) and at least one supporting element (17) interactively connected to said ratchet means such that the interconnection between the connection member and the drive member is released when the dose setting member is turned in the opposite direction.