Anja Smith;Angela Reynolds;Xinyu Zhang;Jon E. Chatterton
发明人:
Anja Smith,Angela Reynolds,Jon E. Chatterton,Xinyu Zhang
申请号：
US13190797
公开号：
US20120029051A1
申请日:
2011.07.26
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Vascular endothelial growth factor A (VEGFA) is a chemical signal produced by cells that stimulates the growth of new blood vessels, and overexpression of VEGFA can lead to undesirable physiological conditions. Through the identification of new siRNA and modifications that improve the silencing ability of these siRNA in vivo, therapeutic compositions and methods have been invented to address the problems associated with this overexpression.
