Kevin Jeffrey Barnham;Paul Stephen Donnelly;Anthony Robert White
发明人:
Kevin Jeffrey Barnham,Paul Stephen Donnelly,Anthony Robert White
申请号：
US12515473
公开号：
US20120270850A1
申请日:
2007.11.20
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention relates to metal complexes, processes for their preparation and their use as pharmaceutical or veterinary agents, in particular for the treatment of conditions in which metal delivery can prevent, alleviate or ameliorate the condition. There are a number of clinical conditions which are caused by or associated with abnormal levels of metals (typically low metal levels). Conditions in of this type include cancer and conditions characterised by or associated with oxidative damage, more specifically neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease or Huntington's disease. The invention also relates to ligands useful in the preparation of metal complexes of this type.
