WALTER RAINER,HAUEL NORBERT,WIEDENMAYER DIETER,PRIEPKE HENNING,KONETZKI INGO,CECI ANGELO,MACK JUERGEN,DOODS HENRI,SCHULER-METZ ANNETTE
申请号：
NZ60119411
公开号：
NZ601194A
申请日:
2011.02.21
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Disclosed herein are compound of general formula I, wherein the variables are defined in the specification, and the use thereof in the treatment of acute pain, visceral pain, neuropathic pain, inflammatory/pain receptor-mediated pain, tumour pain, headache diseases and osteoarthritis. In some embodiments the compound includes (S)-6-oxo-1,6-dihydro-pyridazine-4-carboxylic acid-{ 3-[4-(4-chloro-2-trifluoromethyl-phenylamino)-2-fluoro-benzylcarbamoyl]-tetrahydrofuran-3-yl} -amide, and 6-oxo-1,6-dihydro-pyridazine-4-carboxylic acid-(1-{ [5-(4-fluoro-2-trifluoromethyl-phenylamino)-pyridin-2-ylmethyl]-carbamoyl} -cyclopropyl)-amide.
