Dalton J. Surmeier,Javier Sanchez,Jaime Guzman,Enrico Zampese,Daniel Galtieri,Ema Ilijic
申请号：
US14253528
公开号：
US20140309260A1
申请日:
2014.04.15
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention provides systems, compositions and methods for treatment of dopaminergic disorders (e.g., Parkinsons disease) using the combination of a first compound that inhibits a voltage-gated calcium channel of the type Cav1.3 (e.g., a dihydropyridine such as isradipine), and a second compound that is monoamine oxidase inhibitor and/or is a nitric oxide synthase inhibitor (e.g., rasagiline or derivative thereof).
