Fredrik ELINDER,Peter KONRADSSON,Sara LIIN,Nina OTTOSSON,Wu XIONGYU
申请号:
US15646296
公开号:
US20180193294A1
申请日:
2017.07.11
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to derivatives of dehydroabietic acid useful in treatment of cardiac arrhythmia or a hyperexcitablity disease, such as epilepsy or pain, by extracellularly acting on the voltage sensitive domain (VSD) to open at least one member of the family of voltage-gated Kv (potassium) channels.