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STABLE BROMFENAC SOLUTION
专利权人:
Mandar V. SHAH;SENTISS RESEARCH CENTER
发明人:
Mandar V. SHAH,Prafulla CHAUDHARI,Deepak BAHRI
申请号:
US14898268
公开号:
US20160143869A1
申请日:
2014.06.17
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention provides a stable, aqueous solution comprising bromfenac or a pharmacologically acceptable salt, polymorph, ester or hydrate thereof and/or pharmaceutically acceptable excipients wherein the invention is preferably devoid of an alkyl aryl polyether alcohol type polymer such as tyloxapol, a polyethylene glycol fatty acid ester such as polyethylene glycol monostearate and BAC. Also the present invention is preferably devoid of antioxidants such as sulfite but not limited to sodium sulfite, potassium sulfite and the like. The present invention also provides for a method for treating ocular inflammation and pain, e.g., after cataract surgery, wherein the method comprises topical application of a formulation according to the present invention to the eye of a patient in need thereof.
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