METHOD FOR REMOVING UNMODIFIED HEMOGLOBIN FROM CROSS-LINKED HEMOGLOBIN SOLUTIONS INCLUDING POLYMERIC HEMOGLOBIN WITH A HIGH TEMPERATURE SHORT TIME HEAT TREATMENT APPARATUS

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专利权人:

BILLION KING INTERNATIONAL LIMITED

发明人:

WONG BING LOU,KWOK SUI YI

申请号：

MYPI 2013003924

公开号：

MY162401A

申请日:

2012.04.23

申请国别(地区):

MY

年份:

2017

代理人:

摘要：

A METHOD HEAT TREATMENT OF CROSS-LINKED HEMOGLOBIN SOLUTIONS INCLUDING POLYMERIC HEMOGLOBIN IS DISCLOSED. THE METHOD INVOLVES CONTACTING THE HEMOGLOBIN SOLUTION WITH A HIGH TEMPERATURE SHORT TIME HEAT TREATMENT APPARATUS. THE HIGH TEMPERATURE SHORT TIME PROCESS THERMALLY DENATURES UNMODIFIED TETRAMERIC HEMOGLOBIN (HEMOGLOBIN DIMER FORM), PROTEIN IMPURITIES (E.G. IMMUNOGLOBIN-G, SERUM ALBUMIN), BACTERIA, AND VIRUSES SO THAT RENAL INJURY, VASCULAR DETRIMENTAL EFFECTS AND OTHER TOXICITY REACTIONS CAN BE AVOIDED.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/