LI LIANSHENG,ROMMEL CHRISTIAN,REN PINGDA,CHAN KATRINA,LIU YI,WILSON TROY EDWARD
申请号：
NZ59759510
公开号：
NZ597595A
申请日:
2010.07.15
申请国别(地区):
NZ
年份:
2014
代理人:
摘要：
Chemical entities that modulate phosphatidylinositide 3-kinase (PI3K) activity, pharmaceutical compositions containing the chemical entities, and methods of using these chemical entities for treating diseases and conditions associated with PO kinase activity are described herein. compounds of the disclosure include: (S)-3-(1-(9H-purin-6-ylamino)ethyl)-2-cyclopropyl-8-methylisoquinolin-1(2H)-one, and (S)-3-(1-(9H-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2H)-one.
