Institut de Recherche pour le Developpement (I.R.D.)
发明人:
Lemesre, Jean-Loup,Bras-Goncalves, Rachel,Holzmuller, Philippe
申请号：
AU2012200986
公开号：
AU2012200986A1
申请日:
2012.02.20
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2012200986A120120308.pdf#####MEANS FOR OBTAINING AVIRULENT LEISHMANIA PROMASTIGOTES, PROMASTIGOTES OBTAINED, AND THE APPLICATIONS THEREOF ABSTRACT The invention relates to an expression vector of a gene coding for an anti genic protein of Leishmania promastigote, characterised in that it comprises a PSA gene insert in opposite orientation. The invention can be applied to the development of mutants underexpressing, or no longer expressing, genes coding for an antigenic protein of Leishmania promastigote, and to the therapeutic and/or vaccine-oriented uses thereof.
