Allan Bradley,E-Chiang Lee,Qi Liang,Wei Wang,Anais Legent,Ian Kirby
申请号:
US14056434
公开号:
US20140182003A1
申请日:
2013.10.17
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention discloses methods for the generation of chimaeric human—non-human antibodies and chimaeric antibody chains, antibodies and antibody chains so produced, and derivatives thereof including fully humanised antibodies; compositions comprising said antibodies, antibody chains and derivatives, as well as cells, non-human mammals and vectors, suitable for use in said methods.