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COMPOSITION AND METHOD FOR TREATING COMPLEMENT-MEDIATED DISEASE
专利权人:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人:
SONG, WENCHAO,GULLIPALLI, DAMODAR,MIWA, TAKASHI
申请号:
CA2999299
公开号:
CA2999299A1
申请日:
2016.09.23
申请国别(地区):
CA
年份:
2017
代理人:
摘要:
A recombinant vector having an expression cassette comprising a modified human factor H (hfH) gene is provided, wherein said hfH gene encodes a hfH protein variant comprising SCR1-4, 19-20, and one or more of SCR7, SCR17 and/or SCR18. Also provided are pharmaceutical compositions containing this vector and uses therefor in treating AMD and/or other complement associated diseases.
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