The present invention relates to a method for manufacturing an in vitro vascularized tissue, which enables obtaining the in vitro vascularized tissue by inducing in vitro angiogenesis in a tissue by using vascular cells, for use in in vitro research of diseases in vascularized tissues and developing of a treatment. The method for manufacturing the in vitro vascularized tissue comprises the steps of: supplying to a container for manufacturing tissue a hydrogel in which vascularized tissue cells are mixed submerging a collection tip to which vascular cells are coupled into the hydrogel hardening the hydrogel while the collection tip is submerged and supplying a cell culture fluid to the upper side of the hydrogel.Cette invention concerne un procédé de fabrication dun tissu vascularisé in vitro, qui permet dobtenir le tissu vascularisé in vitro par induction dans un tissu dune angiogenèse in vitro à laide de cellules vasculaires, ledit tissu vascularisé pouvant être utilisé pour la recherche in vitro de maladies dans des tissus vascularisés et la mise au point dun traitement. Le procédé de fabrication du tissu vascularisé in vitro selon linvention comprend les étapes suivantes : lintroduction dans un récipient servant à fabriquer le tissu dun hydrogel dans lequel sont incorporées des cellules de tissu vascularisé limmersion dune pointe de collecte à laquelle des cellules vasculaires sont couplées dans lhydrogel et lintroduction dun liquide de culture cellulaire côté supérieur de lhydrogel.본 발명은 혈관성 조직의 질병을 체외에서 연구하고 치료법을 개발하는데 사용될 수 있도록 체외에서 해당조직을 혈관세포를 이용하여 신생혈관형성을 유도하여 체외 혈관성 조직을 얻을 수 있는 체외 혈관성 조직 제작방법에 관한 것으로, 조직제작용 컨테이너에 혈관성 조직세포가 혼합된 하이드로젤을 공급하는 단계 혈관세포가 부착된 수집팁을 상기 하이드로젤에 침지되는 단계 상기 수집팁이 침지된 상태로 상기 하이드로젤을 경화시키는 단계 및 상기 하이드로젤의 상측으로 세포배양액을 공급하는 단계를 포함한다.
