A method and system enables efficient and robust analysis of pharmacokinetic data. The method includes providing data of a plurality of pharmacokinetic time activity curves (TACs), wherein each pharmacokinetic TAC corresponds to a portion of the pharmacokinetic data generating a first set of parameters of a pharmacokinetic mode!, the first set of parameters providing a first estimate of kinetic parameters of a first pharmacokinetic TAG of the plurality of pharmacokinetic TACs and associating the first set of parameters with a second pharmacokinetic TAG of the plurality of pharmacokinetic TACs, wherein the first set of parameters additionally provides a first estimate of kinetic parameters of the second pharmacokinetic TAG.
