Gary Van Nest;Karen L. Fearon;Dino Dina;Stephen Tuck
发明人:
Gary Van Nest,Stephen Tuck,Karen L. Fearon,Dino Dina
申请号:
US13358492
公开号:
US08669237B2
申请日:
2012.01.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention provides new compositions and methods for immunomodulation of individuals. Immunomodulation is accomplished by administration of immunomodulatory polynucleotide/microcarrier (IMP/MC) complexes. The IMP/MC complexes may be covalently or non-covalently bound, and feature a polynucleotide comprising at least one immunostimulatory sequence bound to a biodegradable microcarrier or nanocarrier.