Federalnoe gosudarstvennoe byudzhetnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "Ryazanskij gosudarstvennyj meditsinskij universitet imeni akademika I.P. Pavlova" Ministerstva zdravookhraneni
发明人:
Mirov Aleksandr Igorevich,Миров Александр Игоревич,Kharkevich Olga Nikolaevna,Харкевич Ольга Николаевна
申请号：
RU2017119819
公开号：
RU0002652894C1
申请日:
2017.06.06
申请国别(地区):
RU
年份:
2018
代理人:
摘要：
FIELD: medicine.SUBSTANCE: invention relates to medicine, namely to obstetrics and gynecology, and can be used to optimize the detection of thrombophilia in women with recurrent reproductive losses. Screening is performed to identify thrombophilia in patients with habitual miscarriage. At the same time, 10 markers of the possible presence of thrombophilia are estimated: the loss of two or more pregnancies in an anamnesis absence of children born alive and/or viable clinically significant thrombosis in the anamnesis the presence in the family history of strokes, heart attacks and coronary heart disease in close relatives under the age of 50 presence in the family history of thrombosis and thromboembolism of the pulmonary artery from the next of kin in the age of up to 50 years pre-eclampsia, eclampsia, HELLP syndrome, severe placental insufficiency, intrauterine growth retardation in the anamnesis severe complications of the postpartum period in the anamnesis: pleuropneumonia, cardiomyopathy clinical manifestations indicating the possible presence of thrombophilia from the central nervous system or gastrointestinal manifestations migraine and venous complications when taking oral contraceptives Alzheimers disease in someone from blood relatives. Each of the markers is estimated as 1 point. With a score of 3 or more, the probability of having thrombophilia is more than 40 %.EFFECT: method allows to isolate a risk group and to improve the diagnosis of congenital and acquired thrombophilia with the habitual loss of pregnancy by evaluating the relevant markers of the possible presence of thrombophilia.1 cl, 2 tblИзобретение относится к медицине, а именно к акушерству и гинекологии, и может быть использовано для оптимизации выявления тромбофилии у женщин с рецидивирующими репродуктивными потерями. Проводят скрининг для выявления тромбофилии у пациенток с привычным невынашиванием беременности. При этом оценивают 10 маркеров возможного наличия тромбофилии: потеря двух и бол
