ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES

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专利权人:

GLENMARK PHARMACEUTICALS S.A.

发明人:

Elias LAZARIDES,Catherine Woods,Mark Bernard

申请号：

US14281101

公开号：

US20140341892A1

申请日:

2014.05.19

申请国别(地区):

US

年份:

2014

代理人:

摘要：

The invention relates to anti-α2 integrin antibodies and their uses. Humanized antibodies are disclosed that bind to the I domain of α2 integrin and inhibit the interaction of α2β1 integrin with collagen. Also disclosed are therapeutic uses of anti-α2 integrin antibodies in treating α2β1-mediated disorders, including anti-α2 integrin antibodies that bind to α2 integrin without activating platelets.

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