Mohammed Benghezal;Tobias Schoep;Alma Fulurija;Douglas E. Berg;Barry J. Marshall
发明人:
Mohammed Benghezal,Tobias Schoep,Alma Fulurija,Douglas E. Berg,Barry J. Marshall
申请号：
US13806084
公开号：
US08992935B2
申请日:
2011.06.24
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The present invention relates to a means of controlling infection persistence of Helicobacter pylori (H. pylori). In particular, the present invention relates to an isolated, genetically modified Helicobacter pylori comprising a functional urease, wherein the contiguous amino acid sequence between amino acid 529 and amino acid 555 of SEQ ID NO:1 is altered to produce said modified Helicobacter pylori which is unable to establish or maintain a persistent infection.
