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COMPOSITION COMPRENANT DES FERMENTS LACTIQUES AMÉLIORÉS DU POINT DE VUE DE L'ADHÉRENCE INTESTINALE PAR ENROBAGE AVEC DE LA FIBROÏNE DE SOIE
专利权人:
CKD Bio Corp.
发明人:
申请号:
EP18781131.0
公开号:
EP3607836A1
申请日:
2018.04.05
申请国别(地区):
EP
年份:
2020
代理人:
摘要:
The present invention relates to a method for improving lactic acid bacteria in survival rate, storage stability, resistance to acid or bile, and adherence to intestinal epithelial cells by coating the surface of lactic acid bacteria with silk fibroin, and a lactic acid bacteria composition prepared therethrough. Conventional techniques construct only a physical protective barrier outside a lactic acid bacteria body by multi-stage coating and thus retain the limitation of being unable to identify an effect on the coherence of lactic acid bacteria to intestinal epithelial cells upon the uptake of the lactic acid bacteria. In contrast, the present invention provides a method in which lactic acid bacteria is coated with silk fibroin extracted from cocoons, whereby the lactic acid bacteria is improved in stability under a storage and distribution condition as well as having remarkably increased stability and intestinal adherence particularly under an intestinal environment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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