Berthet, Francois-Xavier Jacques,Biemans, Ralph,Denoel, Philippe,Feron, Christiane,Goraj, Carine,Poolman, Jan,Weynants, Vincent
申请号:
AU2013201086
公开号:
AU2013201086A8
申请日:
2013.02.22
申请国别(地区):
AU
年份:
2015
代理人:
摘要:
#$%^&*AU2013201086A820150820.pdf#####ABSTRACT The present invention relates to immunogenic compositions and vaccines for the treatment and prevention of Neisserial disease. Immunogenic compositions of the invention contain 5 combinations of antigens selected from at least two different classes of antigens including adhesins, autotransporter proteins, toxins, iron acquisitions proteins and membraneassociated protein (preferably integral outer membrane protein)s. Such combinations of antigens are able to target the immune response against different aspects of the Neisserial life cycle, resulting in a more effective immune response. 10