GILLBERG, PER-GORAN,GUSTAFSSON, NILS OVE,LOVGREN, KURT
申请号：
CA3071182
公开号：
CA3071182A1
申请日:
2018.08.09
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The invention relates to small pellets comprising cholestyramine. The pellets have a high cholestyramine content and are stable enough to be coated with one or more coating layers. The invention also relates to amultiparticulate drug delivery system comprising such pellets.The invention further relates to an oral formulation for targeted delivery of cholestyramine to the colon, comprising a plurality of cholestyramine pellets that are coated with a colon releasecoating. The invention also relates to the use of this formulation in the treatment of bile acid malabsorption and bile acid diarrhoea.
